Tecfidera 120 mg contains dimethyl fumarate, a prescription medicine used in the treatment of multiple sclerosis (MS), specifically relapsing forms of the disease. MS is a chronic condition where the immune system mistakenly attacks the protective covering of nerves, causing a wide range of symptoms. Tecfidera helps reduce the number of relapses and slow down disease progression.

The 120 mg strength is typically used during the initial phase of treatment, followed by a higher maintenance dose as advised by the healthcare provider.

Mechanism of Action

Dimethyl fumarate works by activating a pathway in the body called the Nrf2 (nuclear factor erythroid 2-related factor 2) pathway. This pathway helps protect nerve cells from damage caused by inflammation and oxidative stress, which are thought to contribute to the progression of multiple sclerosis.

By reducing inflammation and protecting nerve tissue, Tecfidera lowers the frequency of flare-ups and helps preserve brain function in people with MS.

Uses

Tecfidera 120 mg is primarily used to treat:

• Relapsing-Remitting Multiple Sclerosis (RRMS)
  This is the most common form of MS, where periods of new or worsening symptoms (relapses) are followed by periods of recovery (remissions)

The medication is not a cure for MS but helps in managing the disease more effectively and maintaining a better quality of life.

Adverse Effects

Common side effects

• Flushing or a warm feeling in the face and body

• Stomach upset, including nausea, diarrhea, or abdominal pain

• Reduced white blood cell count

• Itching or rash