Cacit 500 mg contains capecitabine, an oral chemotherapy medication widely used in the treatment of certain types of cancer. Capecitabine is a prodrug, meaning it becomes active only after being processed in the body. It offers patients the convenience of at-home administration without compromising therapeutic effectiveness. Cacit is often preferred in combination with other cancer treatments or when injectable chemotherapy is not suitable.

Mechanism of Action

Capecitabine is converted into 5-fluorouracil or 5-FU in the body. This active compound interferes with DNA and RNA synthesis by blocking the enzyme thymidylate synthase, which is essential for cell replication. Cancer cells, which multiply rapidly, are especially vulnerable to this interruption. The selective activation of capecitabine in tumour tissue helps target cancer cells more than normal cells, though side effects can still occur.

Uses

Cacit 500 mg is prescribed for the treatment of:

• Colorectal cancer, including both colon and rectal cancer

• Breast cancer, particularly in cases where the cancer is resistant to standard therapies

• Gastric or stomach cancer, often in combination with other agents

• It may also be used in other cancers based on the oncologist’s judgement

  Adverse Effects

  Common Side Effects

  • Tiredness or general weakness

  • Nausea, vomiting, or loss of appetite

  • Diarrhoea

  • Hand-foot syndrome, which may include redness, swelling, or pain in palms and soles

  • Mild skin rashes or dryness

  Hematological Side Effects

  • Decrease in white blood cells, which can raise the risk of infection

  • Reduced red blood cells or anaemia, leading to fatigue