Mitomycin 40 mg contains Mitomycin, an antineoplastic agent used in the treatment of various cancers. Originally derived from a type of soil bacterium, this medication has been a part of cancer therapy for decades. Mitomycin is typically used in combination with other chemotherapy drugs and is administered by a healthcare professional. It is known for its ability to target hypoxic or low-oxygen tumour cells, which are often more resistant to conventional treatments.

Mechanism of Action

Mitomycin acts as an alkylating agent, meaning it binds to DNA and inhibits its function. Once activated inside the body, Mitomycin forms cross-links in DNA strands, preventing cancer cells from dividing and leading to cell death. It is particularly effective in targeting cells that are not actively dividing, including those in low-oxygen environments where other drugs may be less effective. This makes Mitomycin useful in treating tumours with limited blood supply.

Uses

Mitomycin 40 mg is prescribed for the treatment of several types of cancers, including:

• Stomach cancer, especially in advanced stages

• Pancreatic cancer

• Bladder cancer, including use as an intravesical (bladder-administered) therapy

• Non-small cell lung cancer

• Anal cancer, often used alongside radiotherapy

• Other cancers, depending on clinical judgement and treatment protocols

  Adverse Effects

  Common Side Effects

  • Nausea and vomiting

  • Loss of appetite

  • Fatigue or weakness

  • Hair thinning or hair loss

  • Temporary changes in blood cell counts