Innotubilin 120 mg contains docetaxel, a chemotherapy medicine that is commonly used in the treatment of various solid tumors. It is part of the taxane class of anticancer agents and is derived from the needles of the European yew tree. Innotubilin is administered as an intravenous infusion and is known for its ability to slow or stop the growth of cancer cells.

Docetaxel is typically used in combination with other chemotherapy drugs or as a single agent, depending on the type and stage of cancer. It plays a vital role in the treatment of cancers that are advanced, recurrent, or not responding to other therapies.

Mechanism of Action

Docetaxel works by interfering with the microtubule network in cells. Microtubules are structures that help cells divide and maintain their shape. Docetaxel stabilizes these microtubules and prevents them from breaking down, which is necessary for cell division. As a result, the cancer cells are unable to complete mitosis and eventually die.

This action is especially effective in rapidly dividing cells, which makes it a strong option for treating many types of cancers. However, it can also affect some healthy cells, particularly those in the bone marrow, hair follicles, and digestive tract.

Uses

Innotubilin (docetaxel) is used to treat a range of cancers, including:

• Breast cancer, especially after failure of other chemotherapy regimens

• Non-small cell lung cancer, both as a first-line and second-line treatment

• Prostate cancer, particularly metastatic hormone-resistant cases

• Head and neck cancers, usually in combination therapy

• Stomach (gastric) cancer, often used in advanced stages

  Adverse Effects

  Docetaxel can cause side effects, some of which may be manageable while others require careful medical attention.

  Common Side Effects

  • Low white blood cell count, increasing the risk of infection

  • Fatigue or weakness

  • Hair loss, which is usually temporary

  • Nausea or vomiting

  • Mouth sores or inflammation

  • Fluid retention, leading to swelling in the hands, feet, or around the eyes

  • Changes in liver function tests