Degalix 80 mg contains degarelix, a medication used primarily to manage advanced prostate cancer. It is a gonadotropin-releasing hormone (GnRH) antagonist and is administered as a subcutaneous injection. Degarelix is typically given by a healthcare professional in a clinical setting.

Unlike some hormone therapies that initially increase testosterone levels before reducing them, degarelix works quickly to lower testosterone without that initial surge. This helps in avoiding a temporary worsening of symptoms often seen with other treatments. It is a reliable option for men needing prompt hormonal control in prostate cancer.

Mechanism of Action

Degarelix works by blocking the GnRH receptors in the pituitary gland in the brain. Normally, the pituitary signals the testicles to produce testosterone through hormones called luteinising hormone (LH) and follicle-stimulating hormone (FSH).

By directly inhibiting this signal, degarelix causes a rapid reduction in testosterone levels, which helps slow the growth of testosterone-sensitive prostate cancer cells. The medication achieves suppression of testosterone levels within a few days without the initial hormonal flare-up that some other treatments cause.

Uses

Degalix is primarily used for the treatment of:

• Advanced hormone-dependent prostate cancer

• Situations where rapid testosterone suppression is needed to manage disease progression

• Patients who are not suitable for surgical castration or those seeking a reversible treatment approach

  Adverse Effects

  Degalix is generally well tolerated, but like all medications, it may cause side effects. These are usually manageable under medical supervision.

  Common Side Effects

  • Injection site reactions, including pain, redness, or swelling

  • Hot flashes or sweating episodes

  • Weight gain or changes in body fat distribution

  • Fatigue or general weakness

  • Nausea or mild gastrointestinal discomfort