Doxorex contains doxorubicin, a chemotherapy medication that has been widely used for many years to treat various types of cancer. It belongs to a class of medicines called anthracyclines and is often referred to as a cornerstone drug in oncology due to its broad-spectrum activity. Doxorex is administered under medical supervision through intravenous infusion.

Mechanism of Action
Doxorubicin works by interfering with the DNA inside cancer cells. It inserts itself into the DNA strands and inhibits the action of an enzyme called topoisomerase II, which is essential for DNA replication and repair. This leads to breaks in the DNA and eventually causes cancer cell death. It also generates free radicals, which further damage the cancer cells.

Uses
Doxorex is used in the treatment of a wide range of cancers, including breast cancer, blood cancers like leukemia and lymphoma, ovarian cancer, bladder cancer, and certain sarcomas. It is often part of combination chemotherapy regimens to enhance its effectiveness.

Adverse Effects
Common side effects include hair loss, nausea, vomiting, and mouth sores. Many patients experience low blood counts, which can increase the risk of infections or fatigue. Doxorex is known for its potential to cause heart-related side effects, especially with higher cumulative doses, so heart function is usually monitored during treatment. In some cases, the drug may cause a reddish coloration of urine, which is harmless but should be expected.