Gavir contains Ganciclovir, an antiviral medication used to treat and prevent infections caused by cytomegalovirus (CMV), especially in individuals with weakened immune systems. It is commonly prescribed for patients undergoing organ transplants, those with HIV/AIDS, or individuals receiving chemotherapy, as CMV can cause serious complications in such cases. Gavir may be available in injectable or oral formulations depending on the severity of the infection and patient condition.

Mechanism of Action:
Ganciclovir works by interfering with the DNA replication of viruses.

• It enters the infected cells and gets converted into its active form through phosphorylation.

• The active form of Ganciclovir mimics natural DNA building blocks but disrupts viral DNA synthesis when incorporated.

• This stops the virus from multiplying and allows the immune system to control the infection.

  Uses:
  Gavir is used to:

  • Treat active CMV infections, particularly CMV retinitis, a serious eye infection in people with AIDS

  • Prevent CMV disease in transplant patients who are at risk of reactivation or new infection

  • Control CMV infections in other high-risk groups such as cancer patients or newborns with congenital CMV (under specialist care)

    Adverse Effects:
    Gavir is a potent antiviral and, like many powerful medicines, can cause side effects. Common and serious ones include:

    • Bone marrow suppression, leading to low white blood cells, red blood cells, or platelets

    • Nausea, vomiting, or diarrhea

    • Fever or fatigue

    • Kidney problems, especially in patients with pre-existing kidney issues

    • Headache or confusion, particularly with high doses or in sensitive individuals

    • Injection site reactions if given intravenously