Heparin 25000 IU is a high-dose injectable anticoagulant used to prevent and treat blood clots. It belongs to a class of medications known as unfractionated heparins and is commonly used in hospitals to manage conditions like deep vein thrombosis, pulmonary embolism, and to prevent clotting during surgeries or dialysis.

Mechanism of Action:

Heparin works by activating antithrombin, a natural protein in the body that inhibits blood clotting. When antithrombin is activated by heparin, it blocks the action of key clotting factors, particularly thrombin and factor Xa. This prevents new clots from forming and stops existing clots from growing larger. However, it does not break down existing clots.

Uses:

Heparin 25000 IU is used for:

• Treating deep vein thrombosis and pulmonary embolism

• Preventing clot formation in high-risk surgical procedures

• Maintaining patency of catheters and IV lines

• Managing patients with unstable angina or after a heart attack

• Preventing clots during hemodialysis or cardiac surgery

  Adverse Effects:

  Common side effects:

  • Mild bleeding from gums, nose, or injection sites

  • Injection site irritation or bruising

  • Temporary drop in blood platelets