Dextomid contains Dexmedetomidine, a medication primarily used for sedation in medical settings. It is commonly used in intensive care units and during surgical or diagnostic procedures to keep patients calm, drowsy, or asleep without significantly depressing breathing. It provides a balance between comfort and safety in patients requiring monitored sedation.

Mechanism of Action:

Dexmedetomidine acts on the alpha-2 adrenergic receptors in the brain and spinal cord. By stimulating these receptors, it reduces the release of norepinephrine, which leads to sedation, anxiety relief, and pain reduction. Unlike some other sedatives, it has minimal effects on breathing, making it a safer option in certain patient groups.

Uses:

• Sedation in intensive care units, for patients on ventilators

• Procedural sedation during surgeries or diagnostic interventions

• May be used in combination with other anaesthetic agents for balanced anaesthesia

• Sometimes used off-label for sedation in children or palliative care

  Adverse Effects:

  Common side effects:

  • Low blood pressure

  • Slow heart rate

  • Dry mouth

  • Drowsiness