Xeomin is a prescription medicine that contains botulinum toxin type A, used for both cosmetic and therapeutic purposes. It works by temporarily relaxing targeted muscles. It is often compared to other botulinum-based treatments like Botox, but Xeomin is considered a “naked” neurotoxin because it does not contain accessory proteins, which may lower the risk of developing resistance over time.

Mechanism of Action:

Xeomin works by blocking the release of acetylcholine, a chemical messenger that tells muscles to contract. When this signal is blocked, the overactive or tight muscles are relaxed. This effect helps smooth out wrinkles or reduce symptoms caused by muscle spasticity or abnormal movements.

Uses:

Cosmetic Uses:

• To improve the appearance of moderate to severe frown lines (glabellar lines) between the eyebrows

• May also be used off-label for other facial wrinkles

  Therapeutic Uses:

  • Treatment of cervical dystonia (painful neck muscle spasms)

  • Management of blepharospasm (involuntary eyelid twitching)

  • Treatment of upper limb spasticity in adults

  • Other uses may include conditions involving involuntary muscle contractions

    Adverse Effects:

    Most side effects are mild and temporary. They may include:

    • Pain, redness, or swelling at the injection site

    • Headache or tiredness

    • Drooping of the eyelid or brow in cosmetic use

    • Dry eyes or blurred vision

    • Muscle weakness near the injection site