Norsunate contains artesunate, an antimalarial medication derived from artemisinin, a natural compound extracted from the sweet wormwood plant. It is used in the treatment of malaria, particularly the type caused by the Plasmodium falciparum parasite, which is known to be the most dangerous and resistant form of malaria. Norsunate acts quickly to bring down the number of parasites in the blood, making it especially useful in treating severe or complicated malaria cases.

Mechanism of Action

Artesunate works by producing reactive compounds that attack the malaria parasite. Once inside the bloodstream, artesunate is converted into its active form. This active form interacts with iron present in the parasite, creating free radicals that damage the parasite’s internal structures. This leads to rapid killing of the parasite and relief of symptoms such as fever and chills. It is known for its fast action and high effectiveness, especially in the early stages of malaria treatment.

Uses

Norsunate is used for:

• Treatment of uncomplicated malaria caused by Plasmodium falciparum

• Treatment of severe malaria, often as an emergency medicine before switching to other antimalarial drugs

• Rapid reduction of malaria parasite count in the blood

  Adverse Effects

  Norsunate is generally well tolerated, especially when used for short durations. However, like all medicines, it can cause some side effects such as:

  • Dizziness or mild headache

  • Loss of appetite or nausea

  • Abdominal pain or discomfort

  • Low white blood cell count in rare cases

  • Temporary drop in red blood cells after treatment, especially in high parasite load