BDOCIN is a prescription medication that contains the active ingredient colistimethate sodium, which is a form of colistin. It belongs to a group of antibiotics known as polymyxins. BDOCIN is mainly used to treat serious infections caused by certain bacteria that do not respond to other antibiotics. It is often reserved for difficult-to-treat infections, especially those caused by multidrug-resistant organisms in hospital settings.

Mechanism of Action:
Colistimethate sodium, the active component in BDOCIN, works by targeting the outer membrane of certain types of bacteria, particularly Gram-negative bacteria. It binds to the bacterial cell membrane, disrupting its structure and increasing its permeability. This leads to leakage of vital contents from the bacteria, eventually causing the bacterial cell to die. Because of this direct and powerful action, BDOCIN is effective against bacteria that have become resistant to many other antibiotics.

Uses:
BDOCIN is typically used in the treatment of:

• Severe infections caused by multidrug-resistant Gram-negative bacteria

• Hospital-acquired pneumonia, especially ventilator-associated cases

• Bloodstream infections (sepsis) caused by resistant bacteria

• Infections of the urinary tract, abdomen, or skin where other antibiotics have failed

Adverse Effects:
While BDOCIN is effective, it may cause side effects in some patients. The most common concerns are related to the kidneys and nervous system. These include:

• Kidney problems, such as reduced kidney function or increased creatinine levels

• Neurological symptoms like dizziness, numbness, tingling, or muscle weakness

• Breathing difficulties in rare cases when used in high doses

• Pain or swelling at the injection site