Apraize is a medication that contains apremilast, which is used to treat certain chronic inflammatory conditions. It is an oral treatment that helps manage autoimmune disorders by reducing inflammation in the body. Apraize is especially helpful for people with conditions like psoriasis and psoriatic arthritis who need long-term symptom control without using injections or traditional immunosuppressants.

Mechanism of Action:
Apremilast works by targeting an enzyme in the body called phosphodiesterase 4, or PDE4. This enzyme plays a role in regulating inflammation by affecting the levels of specific chemical messengers. By blocking PDE4, apremilast helps increase the levels of a molecule called cyclic AMP, which in turn lowers the production of inflammatory substances like TNF-alpha and interleukins. This results in reduced inflammation, less joint pain, and improvement in skin symptoms.

Uses:
Apraize is commonly prescribed for:

• Treating moderate to severe plaque psoriasis in adults

• Managing active psoriatic arthritis to reduce joint pain and swelling

• Helping improve symptoms in patients who do not respond well to or cannot take other therapies

  Adverse Effects:
  Most people tolerate Apraize well, but some may experience side effects, especially during the early weeks of treatment. These may include:

  • Diarrhea, nausea, or vomiting

  • Headache or fatigue

  • Decreased appetite or unintentional weight loss

  • Mood changes, including low mood or depression in rare cases