Lasix is a well-known medication that contains frusemide, a strong diuretic used to remove extra fluid from the body. It is often prescribed in conditions where the body holds on to too much fluid, such as heart failure, kidney disease, or liver problems. Lasix helps relieve swelling, ease breathing, and lower blood pressure by helping the body get rid of excess water and salt through urine.

Mechanism of Action:
Frusemide acts mainly on a part of the kidney called the loop of Henle. It works by blocking the reabsorption of sodium and chloride, two salts that normally help hold water in the body. When frusemide blocks these salts from being reabsorbed, more salt and water are passed out through the urine. This reduces the amount of fluid in the bloodstream and tissues, helping to lower blood pressure and reduce swelling or fluid in the lungs.

Uses:
Lasix is commonly used for:

• Treating fluid retention or swelling due to heart failure, liver cirrhosis, or kidney problems

• Managing high blood pressure, especially when it is caused or worsened by fluid overload

• Relieving symptoms of pulmonary edema, which is fluid build-up in the lungs

• Supporting urine output in acute kidney issues

  Adverse Effects:
  Frusemide is usually effective, but it can lead to some side effects, especially if fluid or electrolyte levels drop too low. Common side effects include:

  • Frequent urination, which may lead to dehydration

  • Low levels of potassium or sodium, which can cause weakness, cramps, or irregular heartbeat

  • Dizziness or light-headedness due to low blood pressure

  • Muscle cramps or tiredness

  • In rare cases, high doses may affect hearing