Zoster refers to the varicella-zoster virus (VZV) vaccine, primarily used to prevent shingles, a painful skin rash caused by the reactivation of the chickenpox virus. The vaccine is often given to older adults or those with weakened immunity to reduce the risk of shingles and its complications. It helps build protection against the virus and improves quality of life in the ageing population.

Mechanism of Action:
The Zoster vaccine works by stimulating the immune system to recognize and defend against the varicella-zoster virus. The vaccine contains either a weakened live virus (in older formulations) or a recombinant viral protein (in newer versions), which helps the body develop long-term immunity. This reduces the chance of the virus reactivating and causing shingles.

Uses:
Zoster vaccine is used for:

• Preventing shingles in individuals typically over 50 years of age

• Reducing the severity and duration of shingles if it occurs

• Lowering the risk of post-herpetic neuralgia, a common and painful complication of shingles

  Adverse Effects:
  Most side effects of the Zoster vaccine are mild and temporary. These may include:

  • Redness, swelling, or pain at the injection site

  • Headache or muscle aches

  • Tiredness or low-grade fever