Picasa 40 mg contains posaconazole, a broad-spectrum antifungal medication used to prevent and treat serious fungal infections. It is particularly useful for people with weakened immune systems, such as those undergoing chemotherapy, stem cell transplants, or suffering from conditions like HIV/AIDS. Picasa helps protect vulnerable patients from life-threatening infections caused by fungi, including moulds and yeasts, when other antifungal treatments may not be effective.

Mechanism of Action
Posaconazole works by targeting and inhibiting an enzyme in fungi called lanosterol 14-alpha-demethylase. This enzyme is essential for the production of ergosterol, a key component of fungal cell membranes. Without ergosterol, the fungal cell membrane becomes weakened and unable to maintain its structure, causing the contents of the cell to leak out and ultimately leading to the death of the fungal cell.

This action stops the growth and spread of the fungal infection, making it easier for the body’s immune system to clear the remaining pathogens.

Uses
Picasa 40 mg is mainly used for:

• Prevention of invasive fungal infections in high-risk patients, such as those with low white blood cell counts due to chemotherapy or stem cell transplantation

• Treatment of oropharyngeal candidiasis, a fungal infection in the mouth and throat, especially in cases resistant to first-line therapies

• Treatment of invasive infections caused by Aspergillus and Candida species in patients who do not respond well to other antifungals

  Adverse Effects

  Common side effects may include:

  • Nausea or vomiting

  • Diarrhoea

  • Headache

  • Abdominal pain

  • Loss of appetite

  • Fatigue