Pirfenex 400 mg contains Pirfenidone, a medicine used to treat idiopathic pulmonary fibrosis (IPF)—a chronic and progressive lung disease in which the tissue in the lungs becomes thickened and scarred over time, making it difficult to breathe. Pirfenex helps in slowing the progression of this disease.

Mechanism of Action
Pirfenidone works through anti-fibrotic, anti-inflammatory, and antioxidant actions. It reduces the production of substances like transforming growth factor-beta (TGF-β) and tumor necrosis factor-alpha (TNF-α), which are involved in the scarring and inflammation of lung tissues. By blocking these pathways, Pirfenidone helps slow down lung fibrosis and preserve lung function.

Uses
Pirfenex 400 mg is used for:

• Treatment of idiopathic pulmonary fibrosis (IPF) in adults to slow disease progression

• May be used under medical guidance for other fibrotic lung conditions being studied

  Adverse Effects
  Pirfenidone may cause side effects, which are usually manageable:

  • Nausea, loss of appetite, or stomach upset

  • Tiredness or dizziness

  • Skin reactions, especially sensitivity to sunlight, rash, or itching

  • Liver function changes, so regular blood tests are required

  • In some cases, weight loss or gastrointestinal discomfort may occur