Synvisc-One is an injectable treatment that contains hylan G-F 20, a substance similar to the natural fluid found in healthy knee joints. It is used to relieve pain in people with osteoarthritis of the knee who have not found enough relief from simple painkillers or physical therapy. Synvisc-One is given as a single injection directly into the knee joint and provides long-lasting lubrication and cushioning.

Mechanism of Action:
In a healthy joint, synovial fluid acts as a lubricant and shock absorber. In osteoarthritis, this fluid becomes thinner and less effective.

• Synvisc-One works by supplementing the natural joint fluid with a more elastic and viscous form of hyaluronic acid.

• The injected hylan G-F 20 helps restore the cushioning and lubricating properties of the joint fluid.

• This reduces pain, improves mobility, and helps protect the joint from further wear and tear.

  Uses:
  Synvisc-One is used for:

  • Treatment of knee pain caused by osteoarthritis in patients who have not responded well to other therapies such as paracetamol, exercise, or physical therapy.

  • It is given as a single injection and may provide relief for up to six months.

  • It is used in adults only and must be administered by a trained healthcare professional.

    Adverse Effects:
    Most people tolerate Synvisc-One well, but some may experience side effects, such as:

    • Mild pain, swelling, or stiffness at the injection site

    • Fluid buildup in the knee joint or a feeling of warmth

    • Redness or bruising around the injection area

    • Allergic reactions are rare but can occur, especially in people with allergies to bird products like feathers or egg proteins

    • Joint infection or inflammation is extremely rare but serious, and medical help should be sought if severe pain, redness, or swelling develops