Zolmist contains zolmitriptan, a medication used to treat migraine headaches. It belongs to a class of drugs called triptans, which are specifically designed to relieve migraine attacks. Zolmist is available as a nasal spray, allowing for fast absorption and quick relief, especially useful when nausea or vomiting prevents taking tablets. It is not used to prevent migraines but to treat them once they start.

Mechanism of Action:
Zolmitriptan works by acting on serotonin receptors in the brain:

• During a migraine attack, certain blood vessels in the brain become swollen and inflamed.

• Zolmitriptan stimulates serotonin receptors, causing these blood vessels to narrow again and reducing the inflammation.

• This action helps relieve migraine pain and associated symptoms such as sensitivity to light or sound, nausea, and visual disturbances.

  Uses:
  Zolmist is used for:

  • Acute treatment of migraine attacks, with or without aura, in adults.

  • It is especially helpful when rapid onset of action is needed, such as in patients with nausea or early vomiting.

    Adverse Effects:
    While Zolmist is generally well tolerated, some people may experience side effects, including:

    • Unusual sensations like tingling, warmth, or pressure in the face or chest

    • Drowsiness, dizziness, or tiredness, especially after taking the dose

    • Dry mouth or altered taste, due to the nasal spray

    • Throat discomfort, nasal irritation, or stuffy nose may occur shortly after use

    • In rare cases, serious effects like chest pain or increased blood pressure may occur, particularly in those with a history of heart problems